![]() ![]() Channels may be blocked in two ways: (1) QT-prolonging drugs bind to channels and block potassium efflux, (2) genetic defects cause abnormal channels that slow potassium movement, as seen in congenital long QT syndrome. QT interval prolongation occurs when potassium channels facilitating repolarization are blocked.A normal QT c is ≤ 440 ms, and a markedly prolonged QT c is > 500 ms. ![]()
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